Resistance (refusal) insulin usually occurs in people suffering from obesity. But recent studies have found a healthy person even if lack of sleep one night can experience resitensi insulin.
Insulin resistance is a condition where the body's cells become less sensitive to the effects of glucose on insulin reduction. Obesity is one of the causes of insulin resistance.
But according to a new study published in The endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), lack of sleep one night can trigger the occurrence of insulin resistance and type 2 diabetes.
"Bedtime is short on Western society in recent decades, leading to increased prevalence of insulin resistance and type 2 diabetes," said Esther Donga, MD Leiden University Medical Center in the Netherlands and author of the study, as reported from Medicalnewstoday, Friday (7 / 5 / 2010).
According to Donga, the relationship between the increase in the amount of sleep a short time and the prevalence of diabetes may not occur by chance. Findings indicate that a short night's sleep has a greater effect of metabolic regulation on previous findings.
Previous studies have found that the decrease in duration of sleep for several nights lead to disturbances of glucose tolerance.
But studies conducted Donga is the first study that examines the effects of overnight sleep deprivation on insulin sensitivity.
In this study, researchers studied nine healthy people, after a normal night's sleep (about eight hours), and after four hours of sleep a night.
Insulin sensitivity of each study participant was measured using euglycemic hyperinsulinemic clamp method.
This method uses a catheter for infusion of glucose and insulin into the blood stream and then determine insulin sensitivity by measuring the amount of glucose necessary to compensate for increased insulin level without causing hypoglycemia (low blood sugar levels).
"Our data show that insulin sensitivity did not keep people healthy, but depends on the duration of sleep the previous night," said Donga.
Donga said that the negative effects of a short night's sleep on glucose tolerance produced, at least occur only with less sleep a night.
He also added that further research is needed to evaluate whether interventions aimed at improving sleep duration may be useful in stabilizing the glucose levels in patients with diabetes.
Insulin resistance is a condition where the body's cells become less sensitive to the effects of glucose on insulin reduction. Obesity is one of the causes of insulin resistance.
But according to a new study published in The endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), lack of sleep one night can trigger the occurrence of insulin resistance and type 2 diabetes.
"Bedtime is short on Western society in recent decades, leading to increased prevalence of insulin resistance and type 2 diabetes," said Esther Donga, MD Leiden University Medical Center in the Netherlands and author of the study, as reported from Medicalnewstoday, Friday (7 / 5 / 2010).
According to Donga, the relationship between the increase in the amount of sleep a short time and the prevalence of diabetes may not occur by chance. Findings indicate that a short night's sleep has a greater effect of metabolic regulation on previous findings.
Previous studies have found that the decrease in duration of sleep for several nights lead to disturbances of glucose tolerance.
But studies conducted Donga is the first study that examines the effects of overnight sleep deprivation on insulin sensitivity.
In this study, researchers studied nine healthy people, after a normal night's sleep (about eight hours), and after four hours of sleep a night.
Insulin sensitivity of each study participant was measured using euglycemic hyperinsulinemic clamp method.
This method uses a catheter for infusion of glucose and insulin into the blood stream and then determine insulin sensitivity by measuring the amount of glucose necessary to compensate for increased insulin level without causing hypoglycemia (low blood sugar levels).
"Our data show that insulin sensitivity did not keep people healthy, but depends on the duration of sleep the previous night," said Donga.
Donga said that the negative effects of a short night's sleep on glucose tolerance produced, at least occur only with less sleep a night.
He also added that further research is needed to evaluate whether interventions aimed at improving sleep duration may be useful in stabilizing the glucose levels in patients with diabetes.
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